2016 – The Adipocyte in Energy Regulation

Harvard Medical School Division of Nutrition

17th Annual Postgraduate Nutrition Symposium

(when available, video recordings can be accessed by clicking on the lecture title)

Wednesday, July 13th, 2016


Diabetes, Obesity, and the Central Role of the Adipocyte in Maintaining Systemic Homeostasis

Philipp Scherer, PhD, University of Texas Southwestern Medical Center

Session 1:  Molecular Regulation of Adipose Tissue

Moderator:  Lee M. Kaplan, MD, PhD

Adipose Tissue MicroRNAs Constitute a Major Fraction of Circulating Exosomal microRNAs and Modulate Hepatic mRNA Expression

C. Ronald Kahn, MD, Joslin Diabetes Center

Physiological Signaling by Adipose Tissue in Hunger and Energy Homeostasis

Sadaf Farooqi, PhD, University of Cambridge

Discovery of a Novel Class of Naturally-Occurring Lipids with Anti-Diabetic and Anti-Inflammatory Effects

Barbara B. Kahn, MD, Beth Israel Deaconess Medical Center

Roundtable Discussion

Session 2:  Adipocytes in Energy Homeostasis – Lessons from Evolutionary Biology

Moderator:  Alexander A. Soukas, MD, PhD

Cavefish Evolution as a Natural Model for Metabolic Diseases

Nicolas Rohner, PhD, Stowers Institute for Medical Research

Opposing Proteostasis Pathways Drive Thrifty Metabolism and Survival During Nutrient Deprivation

Alexander A. Soukas, MD, PhD, Massachusetts General Hospital

Circadian Rhythms in Adipose Tissue

Jeffrey M. Gimble, MD, PhD, Tulane University School of Medicine

The Mitochondrial Calcium Uniporter: A Key Integrator of Cellular Metabolism

Yasemin Sancak, PhD, Massachusetts General Hospital

Roundtable Discussion

Thursday, July 14th, 2016

 Session 3:  Novel Adipocyte Phenotyping

Moderator: Gökhan S. Hotamisligil, MD, PhD

White, Brown, Beige Fat: Basic Biology and Novel Thermogenic Pathways

Bruce Spiegelman, PhD, Harvard Medical School

Therapeutic Activators of Brown Fat

Aaron M. Cypess, MD, PhD, MMSc, National Institutes of Health

Adipose Tissue and Lipid Imaging

Martin P. Torriani, MD, Massachusetts General Hospital

Insights from Lipidomics

Robert E. Gerszten, MD, Beth Israel Deaconess Medical Center

Metaflammation, Immunometabolism and Metabolic Diseases

Gökhan S. Hotamisligil, MD, PhD, Harvard School of Public Health

Roundtable Discussion

This program was supported by unrestricted educational grants from:

Nutrition Obesity Research Center at Harvard

Harvard Medical School Division of Nutrition

Harvard T.H. Chan School of Public Health

The Conrad Taff Teaching Fund and Taff Family

Mead Johnson Nutrition